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FDA revokes approval of Avastin for breast cancer

The government delivered a blow to some desperate patients Friday as it ruled the blockbuster drug Avastin should no longer be used to treat advanced breast cancer.

Avastin is hailed for treating colon cancer and certain other malignancies. But the Food and Drug Administration said it appeared to be a false hope for breast cancer: Studies haven’t found that it helps those patients live longer or brings enough other benefit to outweigh its dangerous side effects.

Read more: http://www.heraldextra.com/news/science/health-med-fit/medical/fda-revokes-approval-of-avastin-for-breast-cancer/article_f55de3bf-67e9-59bb-b990-8694d857b51e.html#ixzz1eBPrcr8G

If you or a loved one has suffered any of the above serious Avastin side effects, or other serious side effects from Avastin, please contact your doctor immediately.  You are also urged to contact the law firm of Audet & Partners, LLP to protect your legal rights.  You may call us toll-free at 800.965.1461, or you may use this secure form.

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Avastin Information

WARNING: GASTROINTESTINAL PERFORATIONS, SURGERY AND WOUND HEALING COMPLICATIONS, and HEMORRHAGE

Gastrointestinal Perforations

The incidence of gastrointestinal perforation, some fatal, in Avastin‑treated patients ranges from 0.3 to 2.4%. Discontinue Avastin in patients with gastrointestinal perforation.

Surgery and Wound Healing Complications

The incidence of wound healing and surgical complications, including serious and fatal complications, is increased in Avastin‑treated patients. Discontinue Avastin in patients with wound dehiscence. The appropriate interval between termination of Avastin and subsequent elective surgery required to reduce the risks of impaired wound healing/wound dehiscence has not been determined. Discontinue at least 28 days prior to elective surgery. Do not initiate Avastin for at least 28 days after surgery and until the surgical wound is fully healed.

Hemorrhage

Severe or fatal hemorrhage, including hemoptysis, gastrointestinal bleeding, central nervous systems (CNS) hemorrhage, epistaxis, and vaginal bleeding occurred up to five‑fold more frequently in patients receiving Avastin. Do not administer Avastin to patients with serious hemorrhage or recent hemoptysis.

Read more: http://www.drugs.com/pro/avastin.html

If you or a loved one has suffered any of the above serious Avastin side effects, or other serious side effects from Avastin, please contact your doctor immediately.  You are also urged to contact the law firm of Audet & Partners, LLP to protect your legal rights.  You may call us toll-free at 800.965.1461, or you may use this secure form.

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Bevacizumab (trade name Avastin, Genentech/Roche)

Bevacizumab (trade name Avastin, Genentech/Roche) is a drug that blocks angiogenesis, the growth of new blood vessels. It is commonly used to treat various cancers, including colorectal, lung, breast, kidney, and glioblastomas.

Bevacizumab is a humanized monoclonal antibody that inhibits vascular endothelial growth factor A (VEGF-A). VEGF-A is a chemical signal that stimulates angiogenesis in a variety of diseases, especially in cancer. Bevacizumab was the first clinically available angiogenesis inhibitor in the United States.

Bevacizumab was approved by the U.S. Food and Drug Administration (FDA) for certain metastatic cancers. It received its first approval in 2004 for combination use with standard chemotherapy for metastatic colon cancer. While at one point approved for breast cancer by the FDA, the approval was revoked on 18 November 2011.

Read more: http://en.wikipedia.org/wiki/Bevacizumab

If you or a loved one has suffered any of the above serious Avastin side effects, or other serious side effects from Avastin, please contact your doctor immediately.  You are also urged to contact the law firm of Audet & Partners, LLP to protect your legal rights.  You may call us toll-free at 800.965.1461, or you may use this secure form.

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Avastin Side Effects

The commissioner of the Food and Drug Administration recently revoked the approval of the drug Avastin as a treatment for breast cancer.

The commissioner, Dr. Margaret A. Hamburg, said that clinical trials had shown that the drug was not helping breast cancer patients to live longer or to meaningfully control their tumors, but did expose them to potentially serious side effects like severe high blood pressure and hemorrhaging.

IF YOU HAVE SUFFERED ANY OF THE BELOW SERIOUS SIDE EFFECTS, PLEASE CONTACT OUR LAW FIRM NOW TO CONSULT WITH AN ATTORNEY ABOUT YOUR LEGAL RIGHTS. YOU MAY CALL US AT 800.965.1461, OR YOU MAY USE THE SIMPLE AND SECURE FORM ON THE RIGHT HAND SIDE OF THIS PAGE.

Avastin side effects may include:

  • Clotting Issues. Blood clots can travel to the brain and/or lungs causing severe damage and possible death.
  • Wound Healing. Slow or incomplete wound healing of a surgical incision, also potentially fatal.
  • Bleeding that may be severe enough to cause permanent damage to other parts of the body, including the brain. Symptoms of bleeding include vomiting or coughing of blood.
  • Perforations in the Gastrointestinal Tract.
  • The formation of an abnormal passage from parts of the body to another part, sometimes fatal.
  • Stroke or heart problems, which can be fatal. Heart problems include blood clots, mini-stroke, heart attack, and chest pain.
  • Too much protein in the urine, which may lead to serious kidney problems.
  • Serious and sometimes fatal kidney problems (nephrotic syndrome)
  • High blood pressure.
  • Nervous system and vision disturbances. Symptoms may include high blood pressure, headache, seizure, sluggishness, confusion, and blindness.
  • Infusion reactions. These may include high blood pressure or severe high blood pressure that may lead to stroke, difficulty breathing, decreased oxygen in red blood cells, a serious allergic reaction, chest pain, headaches, tremors, and excessive sweating.

If you or a loved one has suffered any of the above serious Avastin side effects, or other serious side effects from Avastin, please contact your doctor immediately.  You are urged to contact the law firm of Audet & Partners, LLP to protect your legal rights.  You may call us toll-free at 800.965.1461, or you may use this secure form.

Important Notice

Persons seeking to preserve any potential legal claims should contact an attorney promptly, since all states have mandatory time periods in which lawsuits must be filed with the courts; otherwise, they may be forever barred.

About Our Firm

Audet & Partners represents individuals, governmental entities, small businesses and institutional shareholders in product liability, tort, negligence, consumer, construction defect, investment fraud, securities, insider trading, antitrust, environmental, whistle blower, aviation and employment cases. In recognition of their outstanding abilities and commitment to the legal profession over the years, the firm and its members have served as Court-appointed Plaintiffs’ Counsel in dozens of federal and state cases throughout the United States.

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Recent Articles

19
Nov
104521457

FDA disallows Avastin as breast-cancer drug

Avastin is no longer approved for treating metastatic breast cancer because it exposes patients to dangerous side effects without any benefit, the U.S. Food and Drug Administration said Friday.

The FDA noted that Avastin’s risks include severely high blood pressure, bleeding, heart attacks, and perforations in such body parts as the nose, stomach, and intestines.

Read more: http://www.philly.com/philly/business/134159658.html#ixzz1eCV7CTP6

19
Nov
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We are a professional, ethical and experienced team of lawyers representing people just like you: individuals who have been seriously injured as the result of Avastin.

Members of our attorney team are recognized nationally as complex litigation specialists in numerous matters. Our record speaks for itself.

To contact us, simply fill out the short form, or call 800.965.1461 to speak directly to an attorney. There is no obligation. No recovery, no charges.

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